Yasunobu Yamashita Selected Research

mepenzolic acid (Cantil)

7/2014	Synthesis and biological comparison of enantiomers of mepenzolate bromide, a muscarinic receptor antagonist with bronchodilatory and anti-inflammatory activities.
3/2014	Superiority of pulmonary administration of mepenzolate bromide over other routes as treatment for chronic obstructive pulmonary disease.
1/2013	Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease.

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Yasunobu Yamashita Research Topics

Disease

11	Neoplasms (Cancer) 01/2022 - 10/2010
6	Pancreatic Neoplasms (Pancreatic Cancer) 05/2022 - 07/2008
4	Chronic Obstructive Pulmonary Disease (COPD) 01/2018 - 01/2013
3	Pulmonary Emphysema 01/2019 - 03/2014
3	Pathologic Constriction (Stenosis) 07/2016 - 01/2010
2	Peritonitis 06/2022 - 03/2021
2	Immune System Diseases (Immune Disorders) 11/2021 - 01/2013
2	Hemorrhage 11/2021 - 07/2012
2	Bile Duct Neoplasms (Bile Duct Cancer) 01/2011 - 01/2010
1	T-Cell Leukemia (Leukemia, T Cell) 04/2022
1	Adenocarcinoma 03/2022
1	Sarcopenia 03/2022
1	Acute Monocytic Leukemia (Acute Monoblastic Leukemia) 11/2021
1	Obesity 11/2021
1	Nervous System Diseases (Neurological Disorders) 11/2021
1	Lymphoma (Lymphomas) 10/2021
1	Cholestasis 03/2021
1	Prostatic Neoplasms (Prostate Cancer) 01/2021
1	Vascular Diseases (Vascular Disease) 01/2021
1	Polyps 01/2021
1	Necrosis 05/2019
1	Gastritis 06/2018
1	Cholangitis 02/2018
1	Mycoses (Diseases, Fungus) 01/2016
1	Stomach Ulcer (Gastric Ulcer) 01/2014
1	Intermittent Claudication 08/2013
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2013
1	Osteomalacia 01/2013
1	False Aneurysm (Pseudoaneurysm) 07/2012
1	Pancreas Divisum 09/2011
1	Pancreatitis 09/2011
1	Cysts 07/2011
1	Neoplasms, Cystic, Mucinous, and Serous 07/2011
1	Jaundice (Icterus) 01/2010
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2010
1	Gallbladder Neoplasms (Gallbladder Cancer) 01/2010
1	Duodenal Obstruction 01/2010
1	Choledocholithiasis 01/2010
1	Lymphatic Metastasis 01/2010

Drug/Important Bio-Agent (IBA)

4	Pancreatic Elastase (Elastase)IBA 01/2019 - 01/2013
3	Gemcitabine FDA Link 05/2022 - 07/2008
3	PlasticsIBA 11/2021 - 01/2010
3	MetalsIBA 03/2021 - 01/2010
3	Muscarinic AntagonistsIBA 01/2019 - 01/2013
3	mepenzolic acid (Cantil)FDA Link 07/2014 - 01/2013
2	130-nm albumin-bound paclitaxelIBA 05/2022 - 03/2022
2	Messenger RNA (mRNA)IBA 11/2021 - 01/2013
2	Pharmaceutical PreparationsIBA 07/2014 - 01/2014
1	snake venom protein C activatorIBA 04/2022
1	Indicators and Reagents (Reagents)IBA 03/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	Histone Deacetylase 6IBA 11/2021
1	A-Form DNA (A-DNA)IBA 11/2021
1	Proteins (Proteins, Gene)FDA Link 11/2021
1	ProdrugsIBA 11/2021
1	RNA (Ribonucleic Acid)IBA 11/2021
1	N-methyladenosineIBA 11/2021
1	Antineoplastic Agents (Antineoplastics)IBA 01/2021
1	TriazolesIBA 01/2021
1	Tiotropium Bromide (Spiriva)FDA Link 01/2019
1	Bronchodilator Agents (Bronchodilators)IBA 01/2018
1	sakuranetinIBA 01/2016
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2015
1	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 07/2014
1	Lansoprazole (Prevacid)FDA LinkGeneric 01/2014
1	Proton Pumps (Proton Pump)IBA 01/2014
1	Alprostadil (Muse)FDA LinkGeneric 08/2013
1	Aquaporins (Water Channels)IBA 01/2013
1	Aldehyde Dehydrogenase 1 FamilyIBA 01/2013
1	VLDL LipoproteinsIBA 01/2013
1	Tartrate-Resistant Acid PhosphataseIBA 01/2013
1	Vitamin D FDA LinkGeneric 01/2013
1	OsteocalcinIBA 01/2013
1	PeriostinIBA 01/2013
1	AngiopoietinsIBA 01/2013
1	Interleukin-1 Receptor Accessory ProteinIBA 01/2013
1	Aggrecans (Aggrecan)IBA 01/2013
1	EnbucrilateIBA 07/2012
1	Ethiodized Oil (Ethiodol)FDA Link 07/2012
1	MucinsIBA 10/2010

Therapy/Procedure

12	Stents 06/2022 - 01/2010
5	Drug Therapy (Chemotherapy) 05/2022 - 07/2008
4	Therapeutics 05/2022 - 07/2008
2	Self Expandable Metallic Stents 11/2021 - 01/2020
2	Adjuvant Chemotherapy 11/2021 - 01/2020
1	Choledochostomy 03/2021
1	Surgical Instruments (Clip) 07/2016
1	Oral Administration 03/2014
1	Ligation 08/2013
1	Gastrectomy 01/2013
1	Argon Plasma Coagulation 01/2012
1	Pancreatectomy 07/2011
1	Combination Drug Therapy (Combination Chemotherapy) 07/2008